Month: <span>February 2025</span>
Month: February 2025

Neural tube defects in a war-torn Tigray regional state of Ethiopia: a retrospective study of 54,626 deliveries

BMC Pregnancy Childbirth. 2025 Feb 3;25(1):108. doi: 10.1186/s12884-025-07254-3. ABSTRACT BACKGROUND: The Tigray region of Ethiopia has a significantly high prevalence of neural tube defects (NTDs), …

MiR-25-3p regulates pulmonary arteriovenous malformation after Glenn procedure in patients with univentricular heart via the PHLPP2-HIF-1α axis

Sci Rep. 2025 Feb 3;15(1):4138. doi: 10.1038/s41598-025-88840-5. ABSTRACT The detailed mechanism of pulmonary arteriovenous malformations after Glenn surgery (G-PAVMs) in cyanotic congenital heart disease (CHD) …

Translaminar synchronous neuronal activity is required for columnar synaptic strengthening in the mouse neocortex

Nat Commun. 2025 Feb 3;16(1):1296. doi: 10.1038/s41467-024-55783-w. ABSTRACT Synchronous neuronal activity is a hallmark of the developing mouse primary somatosensory cortex. While the patterns of …

Reducing radiation exposure in pediatric cervical spine imaging for trauma: a multi-disciplinary quality improvement initiative

Childs Nerv Syst. 2025 Feb 3;41(1):102. doi: 10.1007/s00381-025-06754-z. ABSTRACT PURPOSE: Pediatric cervical spine injury (PCSI) can result in devastating neurologic disability. While computed tomography (CT) …

Gold Mesoporous Silica-Coated Nanoparticles for Quantifying and Qualifying Mesenchymal Stem Cell Distribution; a Proof-of-Concept Study in Large Animals

ACS Appl Bio Mater. 2025 Feb 3. doi: 10.1021/acsabm.4c01714. Online ahead of print. ABSTRACT Mesenchymal stem cells (MSCs) have demonstrated promising therapeutic potential across a …

Model-informed repurposing of eliglustat for treatment and prophylaxis of Shiga toxin-producing Escherichia coli hemolytic-uremic syndrome (STEC-HUS) in children

Pediatr Nephrol. 2025 Feb 3. doi: 10.1007/s00467-025-06688-3. Online ahead of print. ABSTRACT BACKGROUND: Shiga toxin-producing Escherichia coli hemolytic-uremic syndrome (STEC-HUS) is a severe illness predominantly …