Month: <span>February 2025</span>
Month: February 2025

Effectiveness and safety of thiopurines in inflammatory bowel disease patients with NUDT15 polymorphism: a real-world retrospective study

Expert Rev Clin Pharmacol. 2025 Feb 8. doi: 10.1080/17512433.2025.2465425. Online ahead of print. ABSTRACT BACKGROUND: Thiopurine S-methyltransferase (TPMT) and Nudix hydrolase (NUDT15) polymorphisms predispose to …

Improvement of glucocorticoid sensitivity and attenuation of pulmonary allergic reactions by exogenous supplementation with betaine in HDM and LPS-induced allergic mouse model

Clin Transl Allergy. 2025 Feb;15(2):e70039. doi: 10.1002/clt2.70039. ABSTRACT BACKGROUND: Childhood asthma is a heterogeneous disease that exhibits different characteristics and varying severity; however, the metabolite …

Shortening duration of untreated illness in young people with first episode eating disorders: protocol of a randomised controlled feasibility trial of a smartphone friendly multi-modal decision-making tool (FREED-M) to improve help-seeking

Pilot Feasibility Stud. 2025 Feb 7;11(1):14. doi: 10.1186/s40814-024-01585-2. ABSTRACT BACKGROUND: Early intervention gives young people the best chance to recover from eating disorders (EDs). An …

Poor family finances, family-based adverse childhood experiences, and depressive and behavioral symptoms in adolescence

Soc Psychiatry Psychiatr Epidemiol. 2025 Feb 7. doi: 10.1007/s00127-025-02824-4. Online ahead of print. ABSTRACT PURPOSE: Adverse childhood experiences (ACEs) are a possible pathway through which …

Genome data based deep learning identified new genes predicting pharmacological treatment response of attention deficit hyperactivity disorder

Transl Psychiatry. 2025 Feb 7;15(1):46. doi: 10.1038/s41398-025-03250-5. ABSTRACT Although the efficacy of pharmacy in the treatment of attention deficit/hyperactivity disorder (ADHD) has been well established, …