SCN5A variant type-dependent risk prediction in Brugada syndrome
Europace. 2025 Feb 11:euaf024. doi: 10.1093/europace/euaf024. Online ahead of print. ABSTRACT AIMS: The variant in SCN5A with the loss of function (LOF) effect in the …
Month: February 2025
Evinacumab for children with homozygous familial hypercholesterolemia: a plain language summary
Future Cardiol. 2025 Feb 11:1-9. doi: 10.1080/14796678.2025.2461425. Online ahead of print. NO ABSTRACT PMID:39931838 | DOI:10.1080/14796678.2025.2461425
SMC Abca1 and Abcg1 Deficiency Enhances Urinary Bladder Distension but Not Atherosclerosis
Circ Res. 2025 Feb 11. doi: 10.1161/CIRCRESAHA.124.325103. Online ahead of print. ABSTRACT BACKGROUND: Smooth muscle cells (SMCs) regulate blood flow distribution via vasoconstriction mediated by …
Reevaluation of the Impact of the Novel Likely Pathogenic Variant c.1286_1288delAGA in the ATP8A2 Gene: A 7-Year Follow-Up With Clinical, Genetic, and ACMG Insights in an Iranian Family
Mol Genet Genomic Med. 2025 Feb;13(2):e70081. doi: 10.1002/mgg3.70081. ABSTRACT BACKGROUND: Cerebellar ataxia, mental retardation, and dysequilibrium (CAMRQ) syndrome is a rare neurodevelopmental disorder characterized by …
Role of EZH2-mediated abnormal histone H3K27me3 methylation in pressure overload-induced cardiac remodeling in mice
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2024 Sept 28;49(9):1390-1399. doi: 10.11817/j.issn.1672-7347.2024.230335. ABSTRACT OBJECTIVES: Cardiac remodeling is a critical pathological process leading to …
ISG15-Dependent Stabilisation of USP18 Is Necessary but Not Sufficient to Regulate Type I Interferon Signalling in Humans
Eur J Immunol. 2025 Feb;55(2):e202451651. doi: 10.1002/eji.202451651. ABSTRACT Type I interferon (IFN) signalling induces the expression of several hundred IFN-stimulated genes (ISGs) that provide an …
Effects of a school-based physical activity intervention on mental health indicators in a sample of Brazilian adolescents: a cluster randomized controlled trial
BMC Public Health. 2025 Feb 10;25(1):539. doi: 10.1186/s12889-025-21620-y. ABSTRACT PURPOSE: To test the effects of a physical activity intervention program on symptoms of mental disorders …
Emergency Department Mental Health Presentations in Young Children Letter to the Editor “Addressing the Unique Challenges of Paediatric Mental Health Emergency Care” Response
J Paediatr Child Health. 2025 Feb 10. doi: 10.1111/jpc.70005. Online ahead of print. NO ABSTRACT PMID:39930326 | DOI:10.1111/jpc.70005
Psychosocial and mental health in cystic fibrosis in the modern era of care: time to evolve
BMJ Open Respir Res. 2025 Feb 10;12(1):e002606. doi: 10.1136/bmjresp-2024-002606. ABSTRACT Cystic fibrosis (CF) treatment has revolutionised care over the past three decades with major advances …
Relationship between sleep disorders and depressive symptoms among young women in Japan: a web-based cross-sectional study
BMJ Open. 2025 Feb 10;15(2):e089360. doi: 10.1136/bmjopen-2024-089360. ABSTRACT OBJECTIVES: Japanese people are known to get the least amount of sleep in the world, and in …