Inherited genome instability
Science. 2025 Jan 3;387(6729):26-27. doi: 10.1126/science.adu6125. Epub 2025 Jan 2. ABSTRACT Germline structural variants are a risk factor for pediatric extracranial solid tumors. PMID:39745981 | …
Month: January 2025
Network analysis of intergenerational transmission of psychopathological symptom among adolescents: A cross-sectional study
J Fam Psychol. 2025 Jan 2. doi: 10.1037/fam0001289. Online ahead of print. ABSTRACT The intergenerational transmission of psychopathology has been well documented, but limited studies …
APP lysine 612 lactylation ameliorates amyloid pathology and memory decline in Alzheimer’s disease
J Clin Invest. 2025 Jan 2;135(1):e184656. doi: 10.1172/JCI184656. ABSTRACT Posttranslational modification (PTM) of the amyloid precursor protein (APP) plays a critical role in Alzheimer’s disease …
Therapeutic hypothermia in preterm infants under 36 weeks: Case series on outcomes and brain MRI findings
Eur J Pediatr. 2025 Jan 2;184(1):113. doi: 10.1007/s00431-024-05948-y. ABSTRACT PURPOSE: Perinatal hypoxic-ischemic encephalopathy (HIE) is a significant cause of neonatal brain injury. Therapeutic hypothermia (TH) …
RecA deletion disrupts protein homeostasis, leading to deamidation, oxidation, and impaired glycolysis in Cronobacter sakazakii
Appl Environ Microbiol. 2024 Dec 31:e0197124. doi: 10.1128/aem.01971-24. Online ahead of print. ABSTRACT Cronobacter sakazakii is a foodborne pathogen linked to severe infections in infants …
Transcriptomic Profiles in Nasal Epithelium and Asthma Endotypes in Youth
JAMA. 2025 Jan 2. doi: 10.1001/jama.2024.22684. Online ahead of print. ABSTRACT IMPORTANCE: T helper 2 (T2) cells and T helper 17 (T17) cells are CD4+ …
Risk of adverse birth outcomes and birth defects among women living with HIV on antiretroviral therapy and HIV-negative women in Uganda, 2015-2021
J Acquir Immune Defic Syndr. 2025 Jan 2. doi: 10.1097/QAI.0000000000003596. Online ahead of print. ABSTRACT INTRODUCTION: We assessed the risk of adverse pregnancy and birth …
Neuropsychiatric Outcomes in Children and Adolescents with Perinatally Acquired HIV: A Systematic Review and Meta Analysis
J Acquir Immune Defic Syndr. 2025 Jan 2. doi: 10.1097/QAI.0000000000003595. Online ahead of print. ABSTRACT OBJECTIVE: The objective of this study is to define the …
Uncovering Transcriptional Endotypes in Pediatric Asthma-A New Lens on Biomarker-Based Clinical Stratification
JAMA. 2025 Jan 2. doi: 10.1001/jama.2024.26977. Online ahead of print. NO ABSTRACT PMID:39745764 | DOI:10.1001/jama.2024.26977
Pediatric Patient Referred for an Optic Nerve Mass
JAMA Ophthalmol. 2025 Jan 2. doi: 10.1001/jamaophthalmol.2024.5597. Online ahead of print. NO ABSTRACT PMID:39745746 | DOI:10.1001/jamaophthalmol.2024.5597