Month: <span>November 2024</span>
Month: November 2024

A composite scaling network of EfficientNet for improving spatial domain identification performance

Commun Biol. 2024 Nov 25;7(1):1567. doi: 10.1038/s42003-024-07286-z. ABSTRACT Spatial Transcriptomics leverages gene expression profiling while preserving spatial location and histological images. However, processing the vast …

A multiomic atlas identifies a treatment-resistant, bone marrow progenitor-like cell population in T cell acute lymphoblastic leukemia

Nat Cancer. 2024 Nov 25. doi: 10.1038/s43018-024-00863-5. Online ahead of print. ABSTRACT Refractoriness to initial chemotherapy and relapse after remission are the main obstacles to …

Dissecting the novel molecular interactions of solute carrier family 4 member 4 (SLC4A4) for prostate cancer (PCa) progression

Sci Rep. 2024 Nov 25;14(1):29133. doi: 10.1038/s41598-024-72408-w. ABSTRACT Prostate cancer (PCa) is the most common malignancy diagnosed in men. The purpose of this study was …

Haploinsufficiency at the CX3CR1 locus of hematopoietic stem cells favors the appearance of microglia-like cells in the central nervous system of transplant recipients

Nat Commun. 2024 Nov 25;15(1):10192. doi: 10.1038/s41467-024-54515-4. ABSTRACT Transplantation of engineered hematopoietic stem/progenitor cells (HSPCs) showed curative potential in patients affected by neurometabolic diseases treated …