Month: <span>October 2024</span>
Month: October 2024

Assessing solubility of meloxicam in age-specific gastric and intestinal media relevant to adults and pediatric populations: implications for optimizing dosing in patients for postoperative pain

BMC Pharmacol Toxicol. 2024 Oct 9;25(1):75. doi: 10.1186/s40360-024-00799-7. ABSTRACT BACKGROUND: Oral dose formulations must be soluble in gastrointestinal fluids for systemic absorption. The solubility of …

Factors influencing the acceptability of the test, treat and refer practice for malaria among caregivers of under 5 children at community pharmacies and drug shops in Nigeria

Malar J. 2024 Oct 9;23(1):304. doi: 10.1186/s12936-024-05114-7. ABSTRACT BACKGROUND: Malaria affects children under the age of five and pregnant women, leading to high morbidity and …

Ruxolitinib-based regimen in children with autoimmune disease or autoinflammatory disease-related haemophagocytic lymphohistiocytosis

Br J Haematol. 2024 Oct 10. doi: 10.1111/bjh.19803. Online ahead of print. ABSTRACT For autoimmune disease (AD) and autoinflammatory disease (AID)-related haemophagocytic lymphohistiocytosis (HLH) (AD/AID-HLH), …

Factors for Consideration by Pediatric Rheumatologists When Scoring the Physician Global Assessment (PhGA) of Disease Activity in Juvenile Idiopathic Arthritis: First Step Toward an Internal Consensus

Arthritis Care Res (Hoboken). 2024 Oct 10. doi: 10.1002/acr.25447. Online ahead of print. ABSTRACT INTRODUCTION: The Physician global assessment (PhGA) is a tool used nearly …

Prognostic value of red blood cell distribution width-to-albumin ratio in ICU patients with coronary heart disease and diabetes mellitus

Front Endocrinol (Lausanne). 2024 Sep 25;15:1359345. doi: 10.3389/fendo.2024.1359345. eCollection 2024. ABSTRACT BACKGROUND: The red blood cell distribution width (RDW)-to-albumin ratio (RAR) has emerged as a …

Efficacy and Tolerability of Brevilin-A, a Natural JAK Inhibitor, in Pediatric Alopecia Areata: A Case Series

Clin Cosmet Investig Dermatol. 2024 Oct 5;17:2225-2230. doi: 10.2147/CCID.S461557. eCollection 2024. ABSTRACT Alopecia areata represents an autoimmune disease that specifically damages growing hair follicles on …

Increased ketone levels as a key magnetic resonance spectroscopic findings during acute exacerbation in ECHS1-related Leigh syndrome

Radiol Case Rep. 2024 Sep 24;19(12):6292-6296. doi: 10.1016/j.radcr.2024.08.164. eCollection 2024 Dec. ABSTRACT Short-chain enoyl-CoA hydratase, encoded by ECHS1, plays a major role in the valine …