18F-FDG PET/CT Demonstrates Left Adrenal Neuroblastoma in a Pediatric Patient With Beckwith-Wiedemann Syndrome
18F-FDG PET/CT Demonstrates Left Adrenal Neuroblastoma in a Pediatric Patient With Beckwith-Wiedemann Syndrome

18F-FDG PET/CT Demonstrates Left Adrenal Neuroblastoma in a Pediatric Patient With Beckwith-Wiedemann Syndrome

Clin Nucl Med. 2025 Oct 28. doi: 10.1097/RLU.0000000000006190. Online ahead of print.

ABSTRACT

A 2-year-old girl with Beckwith-Wiedemann syndrome (BWS) underwent 18F-FDG PET/CT for differential diagnosis of a left adrenal lesion. The imaging revealed moderate 18F-FDG uptake in the left adrenal gland, accompanied by regional lymphadenopathy. Histopathologic examination confirmed the diagnosis of neuroblastoma. One year following multimodal therapy, follow-up 123I-MIBG SPECT/CT did not demonstrate any abnormal MIBG accumulation. This case highlights the diagnostic and staging utility of 18F-FDG PET/CT in pediatric BWS patients with neuroblastoma.

PMID:41284318 | DOI:10.1097/RLU.0000000000006190